Thyroxine thyrotoxicosis.

Thyroxine-binding prealbumin in thyrotoxicosis and hypothyroidism.

THYROXINE is reversibly bound in the plasma to three proteins: thyroxine-binding globulin (TBG), thyroxine-binding prealbumin (TBPA), and albumin. Changes in the binding capacities of TBG and TBPA in patients with thyroid disease have been reported previously (1, 2). Since starch-gel electrophoresis of serums of patients with thyrotoxicosis indicated a marked decrease in density of the stain in...

Studies of peripheral thyroxine distribution in thyrotoxicosis and hypothyroidism.

Compartmental analysis of the peripheral distribution of labeled thyroxine was applied to various groups of subjects with thyrotoxicosis and hypothyroidism. It was observed that the hepatic incorporation of thyroxine was augmented in subjects with Graves' disease when compared to non-Graves' disease control groups at all levels of thyroid function. Decreased values of hepatic incorporation occu...

Cardiac hypertrophy as a result of long-term thyroxine therapy and thyrotoxicosis.

OBJECTIVES To define the effects of long-term thyroxine treatment upon heart rate, blood pressure, left ventricular systolic function, and left ventricular size, as well as indices of autonomic function, and to compare findings with those in patients with thyrotoxicosis before and during treatment. DESIGN Cross sectional study of patients prescribed thyroxine long term (n = 11), patients with...

Simplified method of drug treatment for thyrotoxicosis using a uniform dosage of methylthiouracil and added thyroxine.

[Serum ratios of triiodothyronine to thyroxine and reverse-triiodothyronine in Graves' disease and destruction-induced thyrotoxicosis].

In order to determine the frequency of thyroxine (T4) toxicosis and study the possibility of usefulness for differentiation between thyrotoxic Graves' disease and destructioninduced thyrotoxicosis, the serum concentrations of T4, triiodothyronine(T3), reverse T3 (rT3), and T4-binding globulin (TBG) and the values of T3-uptake and radioactive iodine uptake (RAIU) were measured, and free, T4 inde...